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Metastatic prostate cancer on the rise since decrease in cancer screenings

Metastatic prostate cancer on the rise since decrease in cancer screenings

A new study from Keck Medicine of USC finds that the incidence rate of metastatic prostate cancer has significantly increased for men 45 and older and coincides with recommendations against routine prostate cancer screenings. “This study is the first to document a continued rise in metastatic prostate cancer using the most up-to-date population dataset,” said

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Novel therapeutic agents may reduce the oncogenesis of metastatic prostate cancer

Novel therapeutic agents may reduce the oncogenesis of metastatic prostate cancer

Researchers have found that treating prostate cancer cells with novel cyclin-dependent kinase 19 (CDK19) and homologous cyclin-dependent kinase 8 (CDK8) inhibitors reduces their potential to migrate into and invade surrounding structures. These molecules may be used as single or combination therapy for patients with advanced disease to prevent and treat metastatic spread. The results appear

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Less prostate cancer screening reduces overdiagnosis but may miss aggressive cases

Less prostate cancer screening reduces overdiagnosis but may miss aggressive cases

Over the past 15 years, public health authorities have downgraded recommendations for the prostate-specific antigen (PSA) test as a screening tool to reduce the overdiagnosis and overtreatment of men with low-grade prostate cancer. Now, researchers from Weill Cornell Medicine have found that while these efforts have been effective, the incidence of higher-grade disease and metastasis

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New combined therapy helps extend lives of men with prostate cancer

New combined therapy helps extend lives of men with prostate cancer

Practice-changing research from Cedars-Sinai Cancer shows that a combination of androgen deprivation therapy — a commonly used hormone injection — plus pelvic lymph node radiation, kept nearly 90% of clinical trial patients’ prostate cancer at bay for five years. The findings were published in the peer-reviewed journal The Lancet. The study also shows that patients

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