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Estrogen-negative cancers respond to anti-estrogenic therapies

Estrogen-negative cancers respond to anti-estrogenic therapies

Anti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor therapies, they halt tumor progression in mice models. Estrogen, a group of female hormones, is known to be involved in cancer progression, especially breast cancer. About 75 % of breast cancers are estrogen-sensitive: they express

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Study confirms racial differences in response to prostate cancer treatment

Study confirms racial differences in response to prostate cancer treatment

A study designed to enroll an equal number of Black and white men with advanced prostate cancer confirms key findings that have been evident in retrospective analyses and suggest potential new avenues for treating Black patients who disproportionately die of the disease. Researchers at Duke Cancer Institute enrolled 50 Black and 50 white men with

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Research into use of diabetes medication for treatment of metastatic prostate cancer

Research into use of diabetes medication for treatment of metastatic prostate cancer

Patients with localised prostate cancer have a good chance of survival, but mortality rates among those with advanced, metastatic forms of the condition remain high. Until now, the precise mechanism behind the spread of the tumour has not been fully explained. But an international research team headed by MedUni Vienna has succeeded in decoding the

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New insights into androgen's action could boost battle against prostate cancer

New insights into androgen's action could boost battle against prostate cancer

Researchers at UVA Cancer Center have unveiled important new insights into how hormones known as androgens act on our cells — and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast cancers. The findings shed light on how androgens interact with their receptors inside cells to affect gene activity. This

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Anti-androgen therapy can fuel spread of bone tumors in advanced prostate cancer

Anti-androgen therapy can fuel spread of bone tumors in advanced prostate cancer

Dr Bock, under the mentorship of Distinguished Professor Dietmar Hutmacher, from QUT Centre for Biomedical Technologies, has focused her research on bone metastases from breast and prostate cancers. She developed 3D miniature bone-like tissue models in which 3D printed biomimetic scaffolds are seeded with patient-derived bone cells and tumour cells to be used as clinical

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Patients helping researchers to advance treatments for prostate cancer

Patients helping researchers to advance treatments for prostate cancer

Researchers at Monash University have established one of the world’s largest collections of living tumours from prostate cancer patients, accelerating the testing of new treatments for prostate cancer and leading to faster patient benefit. One of the most common cancers, prostate cancer is also one of the most difficult to study in the laboratory, with

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