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Staying young, from the cells on up

Staying young, from the cells on up

Researchers at Université de Montréal and McGill University have discovered a new multi-enzyme complex that reprograms metabolism and overcomes “cellular senescence,” when aging cells stop dividing. In their study published today in Molecular Cell, the researchers show that an enzyme complex named HTC (hydride transfer complex) can inhibit cells from aging. “HTC protects cells from […]

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Studies biased toward genomes of people with European ancestry still predict cancer risk in diverse groups, research finds

Studies biased toward genomes of people with European ancestry still predict cancer risk in diverse groups, research finds

Data sets that are biased by having too many genomes from people with European ancestry can still be applied to other ancestry groups to predict their risk of developing breast and prostate cancer. Lars Fritsche of the University of Michigan and colleagues report these findings in a new study published Sept. 16 in PLOS Genetics.

Studies biased toward genomes of people with European ancestry still predict cancer risk in diverse groups, research finds Read More »

Metastatic prostate cancer comes in two forms, which could guide treatment

Metastatic prostate cancer comes in two forms, which could guide treatment

Scientists have identified two subtypes of metastatic prostate cancer that respond differently to treatment, information that could one day guide physicians in treating patients with the therapies best suited to their disease. Building off of earlier studies that discovered clinically relevant subtypes of breast cancer and non-metastatic prostate cancer, researchers identified genetic signatures that can

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Research shows exercise-related proteins can suppress tumor growth

Research shows exercise-related proteins can suppress tumor growth

Forget bedrest, research from Edith Cowan University (ECU) has shown exercise may be a key weapon in cancer patients’ battle against the disease. Exercise causes muscles to secrete proteins called myokines into our blood — and researchers from ECU’s Exercise Medicine Research Institute have learned these myokines can suppress tumour growth and even help actively

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‘Gut bugs’ can drive prostate cancer growth and treatment resistance

‘Gut bugs’ can drive prostate cancer growth and treatment resistance

Common gut bacteria can fuel the growth of prostate cancers and allow them to evade the effects of treatment, a new study finds. Scientists revealed how gut bacteria contribute to the progression of advanced prostate cancers and their resistance to hormone therapy — by providing an alternative source of growth-promoting androgens, or male hormones. Hormone

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Targeted prostate cancer screening could benefit men with inherited cancer syndrome

Targeted prostate cancer screening could benefit men with inherited cancer syndrome

Men who inherit an increased risk of cancer through ‘Lynch syndrome’ could benefit from regular PSA testing from age 40 to detect early signs of prostate cancer, researchers believe. Lynch syndrome raises the risk of several cancer types including most famously bowel cancer, and affects 175,000 people in the UK — although only 5 per

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Study links gut microbiome and aggressive prostate cancer

Study links gut microbiome and aggressive prostate cancer

Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. Findings from the study were published in Cancer Epidemiology, Biomarkers & Prevention. While more research will be necessary, the study’s lead author Nima Sharifi, M.D., says findings

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Prostate cancer urine test identifies good prognosis patients

Prostate cancer urine test identifies good prognosis patients

Researchers at the University of East Anglia have shown that a prostate cancer urine test can identify men at ‘intermediate risk’ who can safely avoid immediate treatment and benefit from ‘active surveillance’ instead. A new pilot study published today reveals how urine biomarkers can show the amount of significant cancer in a prostate, highlighting with

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New prostate cancer biomarkers provide hope to millions of men

New prostate cancer biomarkers provide hope to millions of men

University of South Australia researchers have identified three new biomarkers for prostate cancer to help identify and differentiate potentially aggressive cases of the disease which kills more than 300,000 men each year. An international team of scientists led by UniSA Professor of Molecular Medicine Doug Brooks has made the breakthrough, which assists pathologists when visualising

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New strategy against treatment-resistant prostate cancer identified

New strategy against treatment-resistant prostate cancer identified

Many patients with prostate cancer are treated with drugs that lower or block hormones that fuel tumor growth. While the drugs are effective for a time, most patients eventually develop resistance to these therapies. A new study from Washington University School of Medicine in St. Louis has identified an RNA molecule that suppresses prostate tumors.

New strategy against treatment-resistant prostate cancer identified Read More »

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